Visiting Rome Sep

Hi Team Rome!

Planning to Tour Rome next month for a very short tour and intend to visit the main tourist attractions.

Was wondering if it is possible to do a day return trip from Rome to Pisa?
If so, how can i go about booking the tour? Any recommendations of tour companies or web links would be appreciated.

Also will there be any Internations event in the city around Protected content ?

Looking forward to the trip!

Cheers,
Monica