Exploring the Brain–Microbiome Link (Spa) Registration Required

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Communication between the body’s microorganisms (microbiota) and the developing organism is very important for health before and after birth. During pregnancy, the mother’s microbiota, and later the one the baby acquires during birth and in the first months of life, influence key aspects such as the immune system, metabolism, and the development of organs, including the brain.

Studies in animals show that these microorganisms can change how genes, hormones, and the body’s defenses work in very early stages of life. Although much of the evidence comes from these studies, there is growing data in humans suggesting that these early interactions have long-lasting effects on health, brain development, and the risk of future diseases.

Better understanding this process could help create early interventions to support healthy development and prevent long-term problems.